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Puffballs are white, ball-like creatures who appear as stage enemies on stage 3 of the PC-98 game Story of Eastern Wonderland. Near the end of the stage, they'll come onto the screen from the top and hone their bodies somewhat directly at Reimu Hakurei and Genjii. They take a bullet to be defeated, but they are non-trivial to deal with because if they reach the bottom of the screen, then they'll home directly at Reimu again. If defeated on Lunatic, they'll throw bullets directly at Reimu as return fire. They're combined with red Blood-Vessel Yin-Yang Orbs to form a sort of obstacle.